[The mechanism of inhibition of the activation of the complement first component by polyanions and polycations ].

Abstract

Polyethyleneimine (PEI, 50 kDa) and polymethacrylic acid (PMA, 200 kDa) were shown to inhibit the lysis of sheep erythrocytes induced by the guinea pig complement. They twofold suppress the hemolysis at the concentrations of 0.47 and 0.89 microgram/ml, respectively. The inhibitory effect on the binding of the C1q subunit of human complement to the… (More)

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@article{Burdelev2003TheMO, title={[The mechanism of inhibition of the activation of the complement first component by polyanions and polycations ].}, author={O. O. Burdelev and Alexander P Kaplun and Leonid V. Kozlov and S. V. Lysakova and V L D'iakov and Vitaly I Shvets}, journal={Bioorganicheskaia khimiia}, year={2003}, volume={29 2}, pages={159-62} }