[The investigation of JAK2 V617F point mutation in myeloproliferative disorders by allele-specific polymerase chain reaction in combination with sequence analysis].

Abstract

OBJECTIVE To study the JAK2 V617F point mutation in myeloproliferative disorders (MPD) and explore the clinical significance. METHODS We used Allele-specific polymerase chain reaction (AS-PCR) in combination with sequence analysis to detect the mutation in genomic DNA of peripheral blood mononuclear cells from 20 chronic myelogenous leukemia (CML… (More)

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Cite this paper

@article{Zhang2007TheIO, title={[The investigation of JAK2 V617F point mutation in myeloproliferative disorders by allele-specific polymerase chain reaction in combination with sequence analysis].}, author={S. Sarah Zhang and Wei-da Li and Jun-Hong Song and Wei Xu and Hong-xia Qiu and Jianyong Li}, journal={Zhonghua yi xue za zhi}, year={2007}, volume={87 30}, pages={2109-12} }