[The immunomodulating capacity of Shigella flexneri 2A bacteria that have lost their invasiveness plasmid].


An immunosuppressive effect produced by live microbial cells of S. flexneri virulent plasmid-carrying strain 2a 516 (pSF 140-) was shown in relation to the formation of splenic cells producing antibodies to heterologous antigen (sheep red blood cells). This effect was most pronounced at an early period (days 4-7) after the infection of mice. On the contrary… (More)