[The immunological profile of children with Down's syndrome].

  title={[The immunological profile of children with Down's syndrome].},
  author={Massimo Colombo and E Girardo and Michele B Saitta and B M Ricci and D. Maina},
  journal={Minerva pediatrica},
  volume={41 1},
In 1965 Benda demonstrated that bioptic and autoptic material of children with Down's syndrome showed hypoplasia of the thymus with poor histological differentiation between the cortex and medulla and impairment of Hassal's corpuscles which were also fewer than normal. In the seventies studies revealed the increased susceptibility to infections and higher… CONTINUE READING