[The factor V Leiden mutation in users of hormonal contraceptives].

  title={[The factor V Leiden mutation in users of hormonal contraceptives].},
  author={J. Paseka and V{\'i}t Unzeitig and David Cibula and Alena Bulikov{\'a} and Miloslava Mat{\'y}{\vs}kov{\'a} and Karel Chroust},
  journal={Ceska gynekologie},
  volume={65 3},
OBJECTIVE To assess the frequency of factor V Leiden in oral contraceptive users and to define possible anamnestic data that could predict the presence of factor V Leiden. METHODS Between 1997 and 1998, 583 users of oral estrogen-progestin contraceptives with no history of thrombotic disease were examined. Factor V Leiden was assessed by PCR after isolating DNA from a peripheral venous blood sample. Among other factors, such things as a family history of thromboembolic disease, myocardial… CONTINUE READING