[The expression of mutant p53 (mp53) protein in rat hepatic preneoplastic lesions induced by diethylnitrosamine (DEN)].

Abstract

OBJECTIVE To study p53 genes related to hepatocarcinogenesis. METHODS Using immunohistochemistry techniques, the relation between expression of mp53 protein, placental glutathione S-transferase (GST-P) and the cell proliferative activity was investigated in rat hepatic preneoplastic lesions induced by DEN and the control liver. RESULTS Two of five rats… (More)

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