[The endocannabinoid system and its role in regulation of metabolism in peripheral tissues].


The endocannabinoid system (ECS) comprises cannabinoid receptors (CB1R and CB2R), endogenous lipid ligands (endocannabinoids) and enzymes that synthesize and degrade these compounds. ECS is involved in the regulation of lipogenesis and fatty acids utilization in liver, skeletal muscle and adipose tissue. Activation of CB1 receptor leads to: (i) increase in… (More)


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