• Medicine, Chemistry
  • Published in Nihon Geka Gakkai zasshi 1986

[The effects of serum from tumor-bearing mice on mitogen-induced blastogenesis of normal spleen cells].

@article{Tsuchiya1986TheEO,
  title={[The effects of serum from tumor-bearing mice on mitogen-induced blastogenesis of normal spleen cells].},
  author={Koichiro Tsuchiya and Terukazu Tanaka and Seishiro Inaba and Shinhachiro Nomi and Kenichiro Hamagashira and Hideki Hamada and Takahiro Oka},
  journal={Nihon Geka Gakkai zasshi},
  year={1986},
  volume={87 3},
  pages={
          266-72
        }
}
In order to detect the serum immunosuppressive factors of tumor bearer, the effects of normal C3H/He mice serum (NMS), serum from methylcholanthrene induced fibrosarcoma bearing mice (F4w serum) and sera fractionated by high performance liquid chromatography (HPLC) using anion exchange column were examined on mitogen-induced blastogenesis of normal murine spleen cells (Nspc). The addition of 5% of NMS suppressed the blastogenesis of Nspc. Less than 0.6% of F4w serum suppressed the blastogenesis… CONTINUE READING