[The effects of calmodulin and it's antagonist, W-7, on the acrosome reaction and fertilization of human spermatozoa].

Abstract

The acrosome reaction of mammalian spermatozoa has been shown to be dependent upon an influx of Ca2+ following capacitation. Recently it was shown that calmodulin which activates various enzymatic activities in a calcium-dependent manner is contained in the acrosomal portion of sperm obtained from diverse species including human. Therefore calmodulin… (More)

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