[The effect of various structural features in molecules of derivatives of pyrene and its heterocyclic analogs on its mutagenic activity].


The mutagenic potency of five acetyl and acetylamine derivatives of nitropyrene and 15 heterocyclic analogues of pyrene was studied in the strain Salmonella typhimurium TA1538. A significant impact of the electron-withdrawing acetyl group in the para-position on the mutagenic activity of derivatives of nitropyrene was shown. The para position of nitro and… (More)