[The effect of khellin and timefurone on secretion and catabolism of lipoproteins by cultured human and rabbit hepatocytes].
@article{Volgushev1990TheEO, title={[The effect of khellin and timefurone on secretion and catabolism of lipoproteins by cultured human and rabbit hepatocytes].}, author={S. A. Volgushev and V. Kosykh and E. A. Podrez and D. Novikov and I. Fuki and R. Karpov and V. Repin}, journal={Biokhimiia}, year={1990}, volume={55 2}, pages={ 346-51 } }
Using human and rabbit hepatocyte cultures, the effects of khellin and timefurone on lipoprotein metabolism were studied with special reference to the following parameters: i) binding and degradation of 125I-labeled low density lipoproteins (LDL); ii) apoprotein B (apo-B) secretion measured by immunoenzymatic assay, iii) [35S]methionine labeled apo-B and apo-E within the composition of very low density lipoproteins (VLDL); iiii) total cholesterol synthesis and cholesterol secretion within the… CONTINUE READING