[The effect of controlled mechanical ventilation on the diaphragm of rats].

@article{Yan2009TheEO,
  title={[The effect of controlled mechanical ventilation on the diaphragm of rats].},
  author={Xi-xin Yan and Bei-bei Song and Li-jun Ding and Ling Si and Ji-tao Guan},
  journal={Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases},
  year={2009},
  volume={32 2},
  pages={103-6}
}
OBJECTIVE To investigate the effect of controlled mechanical ventilation (CMV) on the diaphragm of rats, and therefore to understand the theoretic basis of difficulty weaning due to dysfunction and morphology in diaphragm induced by inappropriate mechanical ventilation. METHODS Twenty-four adult male SD rats were randomly assigned into 3 experimental groups: a control group, a 18 h CMV group, and a 24 h CMV group. Trans-diaphragmatic pressure (Pdi), maximal trans-diaphragmatic pressure… CONTINUE READING