• Corpus ID: 6206285

[The effect of carnosine on synaptic transmission in the frog neuromuscular junction].

@article{Drabkina1990TheEO,
  title={[The effect of carnosine on synaptic transmission in the frog neuromuscular junction].},
  author={T. M. Drabkina and V K Radziukevich and S A Shtan'ko},
  journal={Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova},
  year={1990},
  volume={76 1},
  pages={
          18-25
        }
}
The influence of carnosine on quantal content of the e.p.p. of the frog cutaneous pectoris muscle was studied. The e.p.p. quantal content decreased in presence of carnosine (8 mmol/l). Removal of carnosine from the incubation medium potentiated synaptic transmission as compared with its level prior to addition of carnosine to the medium (after-potentiation). Depressant presynaptic action of carnosine did not depend on external Ca+2 concentration or initial level of evoked quantum secretion…