[The effect of RU486 and progesterone on luteal function during pregnancy].

@article{Yamabe1989TheEO,
  title={[The effect of RU486 and progesterone on luteal function during pregnancy].},
  author={Shigeru Yamabe and Kazuaki Katayama and Manabu Mochizuki},
  journal={Nihon Naibunpi Gakkai zasshi},
  year={1989},
  volume={65 5},
  pages={497-511}
}
In order to investigate the role of progesterone in the maintenance of pregnancy, an anti-progesterone agent, RU486 (RU) was injected subcutaneously into pregnant rats on day 12 (D12), and morphological changes of the uterus as well as endocrinological changes were observed. In all rats injected with RU, abortion occurred with macroscopic and microscopic… CONTINUE READING