[The concentration of noradrenalin and adrenalin in isolated sections of the heart].

@article{Muscholl1959TheCO,
  title={[The concentration of noradrenalin and adrenalin in isolated sections of the heart].},
  author={Erich Muscholl},
  journal={Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie},
  year={1959},
  volume={237},
  pages={
          350-64
        }
}
  • E. Muscholl
  • Published 1959
  • Biology, Medicine
  • Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie
1. A method for the assay of noradrenaline and adrenaline in small pieces of heart tissue is described. The amines were extracted with acid ethanol and separated by paper chromatography. The regions containing the amines were eluted and the amount of amines in the eluates was determined by bioassay. Noradrenaline was assayed on the blood pressure of the pithed rat. Adrenaline was assayed on the isolated atropinized rat's uterus stimulated with oxytocin. 2. The identity of the… 
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EVIDENCE FOR NORADRENALINE AND ADRENALINE AS SYMPATHETIC TRANSMITTERS IN THE CHICKEN
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It was found that the cardio‐vascular potency of noradrenaline, as reflected by the increases in heart rate, cardiac tension development and arterial blood pressure, was not significantly different from that of adrenaline.
RELEASE OF CATECHOLAMINES FROM THE HEART
Effect of cocaine and related drugs on the uptake of noradrenaline by heart and spleen.
  • E. Muscholl
  • Biology, Medicine
    British journal of pharmacology and chemotherapy
  • 1961
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It was concluded that cocaine specifically prevented the uptake of noradrenaline by tissues, thus increasing the amount of norADrenaline available for combination with adrenergic receptors.
Catecholamine release from the isolated perfused adrenal gland
TLDR
It is concluded that the nature of the releasing agent and not the composition of the adrenal stores plays a decisive role in determining the relative proportion of the amounts of adrenaline and noradrenaline released.
THE EFFECT OF STELLATE GANGLION EXCISION ON THE CATECHOLAMINE CONTENT AND THE UPTAKE OF H3-NOREPINEPHRINE IN THE HEART OF THE CAT.
Untersuchungen über die Noradrenalin-Freisetzung durch Acetylcholin am perfundierten Kaninchenherzen
  • K. Löffelholz
  • Chemistry
    Naunyn-Schmiedebergs Archiv für Pharmakologie und experimentelle Pathologie
  • 2004
SummaryThe following experiments were done in order to study the effects of alterations in the ionic composition of the perfusion fluid of the isolated rabbit heart on the noradrenaline release…
Effect of drugs on the noradrenaline content of brain and peripheral tissues and its significance.
  • S. Sanan, M. Vogt
  • Biology, Chemistry
    British journal of pharmacology and chemotherapy
  • 1962
TLDR
Results show that prolonged administration of the mono-amine oxidase inhibitors pheniprazine and phenylhydrazinobutane raised the noradrenaline content of the brain of rabbits but not that of cats, whereas it raised the Noradrenalin of the ganglia of cats but not (or rarely) that of rabbits.
Regional Distribution of Catecholamines in the Dog Heart
TLDR
It is concluded that no sample of the heart can be considered as representative of the entire organ, and that the catecholamine content of the whole heart cannot be taken as reflecting the concentrations in various specific areas.
The extent of neuronal re-uptake of 3H-noradrenaline in isolated vasa deferentia and atria of the rat
TLDR
Fractional rates were calculated on the basis of a mathematical model of the adrenergic nerve ending for unidirectional outward diffusion, for outward transport and for neuronal re-uptake for 3H-noradrenaline and found that the density of adrenergic innervation is lower in atria than in vasa deferentia.
Die Wirkung von Reserpin auf die Konzentration von Adrenalin und Noradrenalin im Katzenherz
  • E. Muscholl
  • Biology
    Naunyn-Schmiedebergs Archiv für experimentelle Pathologie und Pharmakologie
  • 2004
TLDR
Observations suggest that the adrenaline of the heart behaves differently from that of sympathetic ganglia or postganglionic nerve fibres after an injection of reserpine, while in ganglia and nerve fibre the adrenaline concentration is not significantly affected by reser Pine.
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References

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TLDR
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