[The cloning and analysis of a single gene in Drosophila homologic with human oncogene TTG].

The human TTG/RBTN family is an oncogene family. There are three members in this family: TTG-1/RBTN-1, TTG-2/RBTN-2 and TTG-3/RBTN-3. Two of them, TTG-1/RBTN-1 and TTG-2/RBTN-2 have been isolated at the sites of chromosomal translocations in T-cell leukaemia. This gene family encodes cysteine-rich proteins with two tandem copies of a LIM motif. The function… CONTINUE READING