• Medicine
  • Published in
    Patologicheskaia fiziologiia…
    2011

[The clinical pathophysiology of the early metabolic syndrome: pathogenetic roles of juvenile dyspituitarism, connective tissue dysplasiae and autoimmune thyroiditis].

@article{Stroev2011TheCP,
  title={[The clinical pathophysiology of the early metabolic syndrome: pathogenetic roles of juvenile dyspituitarism, connective tissue dysplasiae and autoimmune thyroiditis].},
  author={Iu I Stroev and Leonid P Churilov and M M Agapov and Iu A Kononova and O M Mudzukova and S. A. Sadov and I Iu Serdiuk},
  journal={Patologicheskaia fiziologiia i eksperimental'naia terapiia},
  year={2011},
  volume={3},
  pages={
          3-14
        }
}
A review of world literature, including authors' original papers, establishes the clinical pathophysiological hypothesis, initially coined in by authors in 2002, about regular transition of adolescent hypothalamic syndrome (obesity with rose striae) with age into early metabolic syndrome, complicated by autoimmune thyroiditis. Some evidences are obtained, that witness for marfanoid phenotype and chronic disequilibrium between local, autacoid-mediated and systemic, hormone-mediated regulation… CONTINUE READING