[The biological function of platelet-derived growth factor-BB in the osteoblast-osteoclast co-culture system].

Abstract

OBJECTIVE To investigate the biological effects of platelet-derived growth factor (PDGF)-BB on the osteoclasts in the osteoblast-osteoclast co-culture system. METHODS The human osteoblasts and osteoclasts were isolated from the iliac crest of patients and co-cultured in the same system. The PDGF-BB or PDGF-BB + NO synthase inhibitor, N(G)-monomethyl-L… (More)

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