[The association of single nucleotide polymorphism of slow delayed rectifier K+ channel genes with atrial fibrillation in Han nationality Chinese].

@article{Zeng2005TheAO,
  title={[The association of single nucleotide polymorphism of slow delayed rectifier K+ channel genes with atrial fibrillation in Han nationality Chinese].},
  author={Zhi-yu Zeng and J. Z. Pu and Chen Tan and Si-yong Teng and Jian-hong Chen and Shao-yong Su and Xiao-yang Zhou and Shuhong Zhang and Yi-shi Li and Fang-zheng Wang and Dongfeng Gu},
  journal={Zhonghua xin xue guan bing za zhi},
  year={2005},
  volume={33 11},
  pages={987-91}
}
OBJECTIVE To investigate the association between atrial fibrillation and the single nucleotide polymorphism (SNP) of slow delayed rectifier K(+) channel (I(Ks)) genes in Han nationality Chinese. METHODS Three hundred and eighty of Han nationality Chinese (142 atrial fibrillation, 120 in-hospital and 118 out-hospital control) were enrolled in this study. Asian specific non-synonymous SNPs of KCNQ1 P448R, KCNQ1 R519H, KCNQ1 G643S, KCNE1 G38S and KCNE1 D85N were genotyped by restriction fragment… CONTINUE READING