Corpus ID: 77494514

[The antitoxic function of the liver in D-galactosamine poisoning].

  title={[The antitoxic function of the liver in D-galactosamine poisoning].},
  author={Vengerovskiĭ Ai and Sedykh Im and Novozheeva Tp and S. As},
  journal={Patologicheskaia fiziologiia i èksperimental'naia terapiia},
  • Vengerovskiĭ Ai, Sedykh Im, +1 author S. As
  • Published 1990
  • Chemistry
  • Patologicheskaia fiziologiia i èksperimental'naia terapiia
  • Two intragastric administrations of 500 mg/kg of D-galactosamine reduce the RNA and the cytochrome P-45, and b5 content in the hepatic microsomes of rats; inhibit the activity of aminopyrine-N-demethylase, hexobarbital hydroxylase, aniline-p-hydroxylase, and glutathione-S-transferase; reduce the rate of NADP.H and NAD.H oxidation; accelerate inactivation of cytochrome P-450 to cytochrome P-420; reduce the number of points of hexobarbital binding with N-octilamine, though increase the… CONTINUE READING
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