[The antioxidant function of high density lipoproteins: a new paradigm in atherosclerosis].

@article{Toms2004TheAF,
  title={[The antioxidant function of high density lipoproteins: a new paradigm in atherosclerosis].},
  author={M Llu{\"i}sa Queralt Tom{\'a}s and G. Herrera Latorre and Mariano Sent{\'i} and Jaume Marrugat},
  journal={Revista espanola de cardiologia},
  year={2004},
  volume={57 6},
  pages={
          557-69
        }
}
The one disease associated with the greatest morbidity and mortality in industrialized countries is coronary heart disease (CHD). High density lipoprotein (HDL) is one of the most important independent protective factors for the arteriosclerosis which underlies CHD. Paraoxonase 1 (PON1) is an enzyme that confers antioxidant properties to HDL. In vitro, PON1 hydrolyzes a large variety of endogenous or exogenous substrates, some of which are clearly involved in the progression of arteriosclerosis… CONTINUE READING
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