[The anti-arrhythmic activity of quinuclidine derivatives].


Experiments on conscious rabbits have shown that the quinuclidine bicarphene displays a sufficiently profound antiarrhythmic activity. The agent, 1.0 mg/kg, prevents and abolishes arrhythmias induced by calcium chloride, strophanthin, and epinephrine and fails to affect the cardiac arrhythmias caused by aconitine and barium chloride. Higher bicarphene doses… (More)