[The adenylate cyclase system of human platelets].

  title={[The adenylate cyclase system of human platelets].},
  author={Natalie Ferry and Serge Adnot and Paul A. Insel and Jacques Hanoune},
  journal={Nouvelle revue francaise d'hematologie},
  volume={25 6},
This review summarizes current knowledge on the adenylate cyclase system of human platelets. In the first part, the main molecular entities of this system are described, emphasis being layed on coupling proteins (Ns, Ni) which transduce the hormonal message from receptors to the catalytic unit. The mechanisms by which regulation of adenylate cyclase occurs is discussed and a comprehensive model is proposed. In the second part, are reviewed the hormonal and non hormonal regulators of the… CONTINUE READING

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