[The Collaborative Cross, a groundbreaking tool to tackle complex traits].

@article{Panthier2012TheCC,
  title={[The Collaborative Cross, a groundbreaking tool to tackle complex traits].},
  author={Jean-Jacques Panthier and Xavier Montagutelli},
  journal={Medecine sciences : M/S},
  year={2012},
  volume={28 1},
  pages={
          103-8
        }
}
Complex traits, like the susceptibility to common diseases, are controlled by numerous genomic regions which individual effect is generally weak. These observations led geneticists to develop an experimental system to dissect the genetic of complex traits in the mouse. The Collaborative Cross (CC) is a genetic reference population of over 300 inbred lines derived from eight inbred strains of three Mus musculus sub-species that captures 90% of the genetic variation known in the mouse genome. We… CONTINUE READING

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