[Teratogenic risk during treatment of Wilson disease].

  title={[Teratogenic risk during treatment of Wilson disease].},
  author={Charles X. Piussan and M V Mathieu},
  journal={Journal de genetique humaine},
  volume={33 3-4},
Untreated Wilson's disease usually causes infertility or abortion, as a result of increased intrauterine copper level. Therefore, a chelation treatment is necessary during the whole pregnancy. The most used is D-Penicillamine whose teratogenic risks such as cutis laxa, dermatopathy or complex mesenchyme abnormalities are paradoxically rare in the new borns… CONTINUE READING