[Systemic photochemotherapy (PUVA) in acanthosis nigricans maligna: regression of keratosis, hyperpigmentation and pruritus].

@article{Bonnekoh1989SystemicP,
  title={[Systemic photochemotherapy (PUVA) in acanthosis nigricans maligna: regression of keratosis, hyperpigmentation and pruritus].},
  author={Bernd Bonnekoh and Barbara Thiele and H F Merk and Gustav Mahrle},
  journal={Zeitschrift fur Hautkrankheiten},
  year={1989},
  volume={64 12},
  pages={1059-62}
}
We report on a 60-year-old patient, who developed malignant acanthosis nigricans (MAN) with intense itching 2 years after a large-cell bronchial carcinoma had been diagnosed and found inoperable. The MAN became manifest at a phase of full clinical remission of the lung tumor, which had been treated with cytostasis (cisplatin, vindesine), high energy irradiation, and extirpation of the lymph node metastases. One year after onset of MAN, the lung tumor relapsed, accompanied by an elevated serum… CONTINUE READING