[Synthesis of lipophilic muramoyldipeptide derivatives].

@article{Kurianov1994SynthesisOL,
  title={[Synthesis of lipophilic muramoyldipeptide derivatives].},
  author={V O Kur'ianov and A E Zemliakov and V Ia Chirva},
  journal={Bioorganicheskaia khimiia},
  year={1994},
  volume={20 4},
  pages={439-47}
}
beta-Glycosides of N-acetylglucosamine, obtained by the oxazoline synthesis, with 2-dodecyltetradecanol-1 and 2,3-didodecyloxypropanol-1 as aglycons, were converted into muramic acids and then coupled with the dipeptide to give lipophilic glycosides of muramoyldipeptide. On the other hand, condensation of 2-dodecyltetradecanyl esters of glycine and 6… CONTINUE READING