[Synthesis of germinal 3,3-dithienyl compounds (author's transl)].

Abstract

A new synthetic approach to the cerebroactive compound (+)-(R)-alpha-[(S)-1-[(3,3-di-3-thienylallyl)amino]ethyl]benzyl alcohol(1) (tinofedrine), its stereoisomers and related derivatives is reported. Several compounds increased blood flow in the arteriae vertebralis and femoralis of anesthesized dog. 

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