[Suppressing effect of isoforskolin and forskolin on ocular hypertension in rabbits].

@article{Li2000SuppressingEO,
  title={[Suppressing effect of isoforskolin and forskolin on ocular hypertension in rabbits].},
  author={Xiaoli Li and Li jia Nie and Wen-Li Yang and Zuji Chen and Xing-rong Wang and Lihui Luo},
  journal={[Zhonghua yan ke za zhi] Chinese journal of ophthalmology},
  year={2000},
  volume={36 4},
  pages={292-4}
}
OBJECTIVE To examine the effects of isoforskolin (isoF) and forskolin (FSK) suspensions administered topically on eyes with ocular hypertension (OHT) and observe the local irritation of the drugs. METHODS The intraocular pressure (IOP) was measured with pneumotonometer in screened spontaneous or water-loading induced OHT rabbits for evaluation of drug effects, and the irritation indices were recorded as well. RESULTS In screened OHT rabbits, isoF significantly lowered IOP from 0.5 to at… CONTINUE READING

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