[Study on the up-regulation of B7 molecules expression and immunogenicity of acute leukemia cells induced by interleukin 7].

OBJECTIVE To investigate the effects of interleukin 7 (IL-7) on B7 molecules expression and immunogenicity of acute leukemia (AL) cells. METHODS The B7 molecules expression on fresh acute leukemia cells and on the IL-7 exposed leukemia cells was detected by FACScan cytometer. B7-1 and B7-2 mRNA in IL-7 treated HL-60 cells were detected by reverse… CONTINUE READING