[Study on the relationship between single-nucleotide polymorphisms in IL-6, IL-10 genes and HBV-related hepatocellular carcinoma].

@article{Qiu2011StudyOT,
  title={[Study on the relationship between single-nucleotide polymorphisms in IL-6, IL-10 genes and HBV-related hepatocellular carcinoma].},
  author={Xiao-qiang Qiu and Chun-hua Bei and Hong-ping Yu and Xiao-yun Zeng and Qiu-an Zhong},
  journal={Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi},
  year={2011},
  volume={32 5},
  pages={510-3}
}
OBJECTIVE To investigate the association between single nucleotide polymorphisms (SNPs) in cytokine IL-6, IL-10 genes and HBV-related hepatocellular carcinoma (HCC). METHODS A hospital-based case-control study was conducted in 381 cases with HBV-related HCC, 340 HBsAg carriers and 359 non-tumor controls. Genotypes of -572 site of IL-6 gene and -819, -592 sites of IL-10 gene were determined by real-time polymorphism chain reaction. Unconditional logistic regression was used to estimate the… CONTINUE READING
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