[Study on the mitochondrial DNA mutations in patients with early-onset diabetes mellitus].

@article{Yu2005StudyOT,
  title={[Study on the mitochondrial DNA mutations in patients with early-onset diabetes mellitus].},
  author={De-Min Yu and Ming-zhen Li and De-min Liu},
  journal={Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics},
  year={2005},
  volume={22 1},
  pages={
          14-7
        }
}
OBJECTIVE To investigate the prevalence of mitochondrial DNA (mtDNA) mutations in patients with early-onset diabetes in Tianjin, and to explore the relationship between mtDNA mutations and diabetes. METHODS 348 non-related patients whose age at onset of diabetes was less than 45 years were randomly recruited, and 207 non-related and non-diabetic subjects were enrolled as controls. All their clinical and biochemical data were collected. Total genome was extracted conventionally from the… CONTINUE READING

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