[Study on the leukocyte-rich plasma as the specimen for the measurement of endotoxin].

@article{Kan2012StudyOT,
  title={[Study on the leukocyte-rich plasma as the specimen for the measurement of endotoxin].},
  author={Shigenori Kan and Gaku Takahashi and Chiaki Onodera and Takuyuki Masuda and Naoya Hamamatsu-shi Matsumoto and Katsuya Inada and Shigeatsu Endo},
  journal={Rinsho byori. The Japanese journal of clinical pathology},
  year={2012},
  volume={60 11},
  pages={
          1045-52
        }
}
PURPOSE In the diagnosis of sepsis, the sensitivity of the endotoxin assay using platelet-rich plasma (PRP) is not as high as expected. In the endotoxin assay using PRP, endotoxin occurring within and on the surface of white blood cells cannot be measured. Thus, we devised a method of preparing leukocyte-rich plasma (LRP) using hydroxyethyl starch (HES) in order to improve the endotoxin assay. METHODS The endotoxin concentration was measured by an endotoxin-specific Limulus amebocyte lysate… CONTINUE READING

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