[Study on the genotoxicity of dibromoacetic acid in drinking water].

  title={[Study on the genotoxicity of dibromoacetic acid in drinking water].},
  author={Caiyun Fang and Yin Ping Wang and Songhui Jiang and Huigang Zhu},
  journal={Wei sheng yan jiu = Journal of hygiene research},
  volume={30 5},
Dibroacetic acid (DBA) is a byproduct of drinking water disinfected by halogenation and it belongs to halogenated acetic acids. It also can be found in ozonated drinking water. Four short-term assays were performed to detect the genotoxic activity of DBA. In the Ames test, DBA showed mutagenic activity in Salmonella typhimurium strain TA100 with or without rat liver-derived metabolic activation system (S9). In UDS test, DBA was found to induce DNA damage in rat primary hepatocyte. Mouse bone… CONTINUE READING
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