[Study on the gene knockout model mice of Duchenne muscular dystrophy].

Abstract

OBJECTIVE With a view to further experimental studies on Duchenne muscular dystrophy (DMD), we investigated the motor function, serum creatine kinase (CK) level and pathological characteristics of muscular tissue in C57, mdx, dystrophin/utrophin gene double knockout (dko)mice. METHODS Gene identification was performed for the filial generation of… (More)

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