[Study on the association between tumor necrosis factor alpha gene polymorphism and systemic lupus erythematosus].

@article{Wang1999StudyOT,
  title={[Study on the association between tumor necrosis factor alpha gene polymorphism and systemic lupus erythematosus].},
  author={Ming-rong Wang and Yi Dong and Shao-qing Huang},
  journal={Zhonghua nei ke za zhi},
  year={1999},
  volume={38 6},
  pages={393-6}
}
OBJECTIVE To examine whether polymorphism within the tumor necrosis factor alpha (TNFalpha) gene is associated with the susceptibility and clinic manifestations to systemic lupus erythematosus (SLE) in the patients of Han ethnic group collected from the Northern China. METHODS TNF(1) and TNF(2) subtypes of TNFalpha gene were defined by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) analysis in 89 Chinese patients with SLE and 70 ethnically matched controls from… CONTINUE READING