[Study on the association between estrogen receptor alpha gene polymorphism and intrahepatic cholestasis of pregnancy].

OBJECTIVE To investigate the relationship between estrogen receptor alpha (ERalpha) gene polymorphism and intrahepatic cholestasis of pregnancy (ICP). METHODS The Xba I and Pvu II polymorphisms in intron 1 of ER alpha gene were detected by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) method in 100 pregnant women with ICP… CONTINUE READING