[Study on anti-angiogenesis effect of three curcumin pigments and expression of their relevant factors].

@article{Huang2015StudyOA,
  title={[Study on anti-angiogenesis effect of three curcumin pigments and expression of their relevant factors].},
  author={Yan-fen Huang and Xue-xin Zhu and Zhi-shan Ding and Gui-Yuan Lv},
  journal={Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica},
  year={2015},
  volume={40 2},
  pages={324-9}
}
To study the in vitro anti-angiogenesis effect of three curcumin pigments (curcumin, demethoxycurcumin, bisdemethoxycurcumin). In the study, the inhibitory effect of the three curcumin pigments on proliferation of HUVEC cells induced by OX-LDL and the effect on migration of HUVEC cells were detected. The effect on neovascularization was observed by chorioallantoic membrane (CAM) test. The effect on cell adhesion factors ICAM-1 and VCAM-1 of HUVECs were tested by Real-time RT-PCR. It was found… CONTINUE READING