[Study on NPM1 gene mutations in childhood acute myeloid leukemia].

@article{Zhou2010StudyON,
  title={[Study on NPM1 gene mutations in childhood acute myeloid leukemia].},
  author={Min Zhou and Jingyan Tang and Hui-liang Xue and Yin Liu and C K Pan and Jing Chen and Lu Dong and Shu-hong Shen},
  journal={Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi},
  year={2010},
  volume={31 7},
  pages={438-41}
}
OBJECTIVE To examine the incidence and clinical significance of NPM1 mutations in childhood acute myeloid leukemia (AML) patients. METHODS NPM1 mutations of 70 newly diagnosed childhood AML were detected by high resolution melting (HRM) analysis on the LightCycler 480. The incidence and clinical significance were analyzed. RESULTS NPM1 mutations were… CONTINUE READING