Corpus ID: 32413674

[Studies on the combined chemotherapy of o-[bis-(2-chloroethyl)-aminomethyl]-phenylalanine dihydrochloride (AT-581) and operation in the treatment of Brown-Pearce carcinoma in the rabbit].

@article{Yang1966StudiesOT,
  title={[Studies on the combined chemotherapy of o-[bis-(2-chloroethyl)-aminomethyl]-phenylalanine dihydrochloride (AT-581) and operation in the treatment of Brown-Pearce carcinoma in the rabbit].},
  author={J. Yang and B. Hsu},
  journal={Yao xue xue bao = Acta pharmaceutica Sinica},
  year={1966},
  volume={13 2},
  pages={
          113-8
        }
}
  • J. Yang, B. Hsu
  • Published 1966
  • Medicine
  • Yao xue xue bao = Acta pharmaceutica Sinica
  • AT-581, o-[bis-(2-chloroethyl)-aminomethyl]-phenylalanine dihydrochloride or ocaphane, is a new antitumour agent synthesized at our Institute. It has a strong inhibitory action on a broad spectrum of experimental tumours. It has also been shown to be effective against some human cancers. In the present paper the combined action of AT-581 and surgery on the Brown-Pearce carcinoma of the rabbit was investigated. 1. When the Brown-Pearce carcinoma cells were inoculated into the testes of rabbits… CONTINUE READING

    Topics from this paper