[Studies on paclitaxel-loaded nanoparticles of amphiphilic block copolymer].

  title={[Studies on paclitaxel-loaded nanoparticles of amphiphilic block copolymer].},
  author={Anjie Dong and Lian-dong Deng and Duo-xian Sun and Yue-ting Zhang and Jian-zhou Jin and Yingjin Yuan},
  journal={Yao xue xue bao = Acta pharmaceutica Sinica},
  volume={39 2},
AIM To investigate the paclitaxel-loaded nanoparticles of poly(ethylene glycol)-b-poly(D,L-lactic acid) amphiphilic diblock copolymer (PMT). METHODS PMT was prepared by solid dispersion technique. The average size and size distribution were determined by dynamic light scattering (DLS). The morphology was characterized by transmission electron microscopy (TEM) and 1HNMR. The influences of the copolymer molecular weight and the paclitaxel-fed amount on PMT were studied. Therapeutic effect of… CONTINUE READING
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