[Studies on liver-toxicity in rhigoma of Dioscorea bulbifera].

  title={[Studies on liver-toxicity in rhigoma of Dioscorea bulbifera].},
  author={Xing-qi Tan and Jin-lan Ruan and Hai-sheng Chen and Ju-ying Wang},
  journal={Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica},
  volume={28 7},
OBJECTIVE To explore the liver-toxic fraction in Rhigoma of Dioscorea bulbifera. METHOD The rats were randomized into four groups: control group (20% PVP-water), T001(10% total methanol extraction), F002(5% chloroform fraction) and F003(5% methanol fraction). Direct bilirubin (DBil) and Glutamic-pyruvic transaminase (GPT) were examined, and liver index was measured. The histological and morphological observations were performed with optical and electrical microscope. RESULT T001 and F002… CONTINUE READING