[Studies on gene expression and the 5' CpG islands methylation status of E-cadherin in acute myeloid leukemia].

Abstract

OBJECTIVE To study the relationship between E-cadherin gene expression and the methylation status of E-cadherin 5' CpG islands in acute myeloid leukemia (AML). METHODS Reverse transcription-PCR (RT-PCR), flow cytometry and methylation specific PCR were used to analyze the E-cadherin gene and protein expression and its 5' CpG island methylation status… (More)

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