[Studies on efficacy and safety of panipenem/betamipron against infections in pediatrics and on its movement to cerebrospinal fluid including cases of penicillin-resistant Streptococcus pneumoniae meningitis].

Abstract

The efficacy and the safety of panipenem/betamipron (PAPM/BP), a new carbapenem antibiotic against infections in pediatrics were studied. The obtain results are summarized as follows. 1. The transfer of PAPM/BP to cerebrospinal fluid (CSF) was studied in 2 cases of purulent meningitis. The PAPM/BP levels in CSF in a dose 26.1 mg/kg peaked at 3.21 micrograms… (More)

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@article{Haruta1992StudiesOE, title={[Studies on efficacy and safety of panipenem/betamipron against infections in pediatrics and on its movement to cerebrospinal fluid including cases of penicillin-resistant Streptococcus pneumoniae meningitis].}, author={Tsutomu Haruta and Kazuhiro Ohkura and Shunsuke Kuroki and Hideki Nikami and Mayumi Naramura and T. Nishio and Y. Kobayashi}, journal={The Japanese journal of antibiotics}, year={1992}, volume={45 4}, pages={416-23} }