Corpus ID: 20029566

[Studies on antifertility constituents of Siegesbeckia glabrescens Mak].

  title={[Studies on antifertility constituents of Siegesbeckia glabrescens Mak].},
  author={X. Y. Dong and M. Chen and W. Jin and D. X. Huang and S. Shen and H. Li},
  journal={Yao xue xue bao = Acta pharmaceutica Sinica},
  volume={24 11},
  • X. Y. Dong, M. Chen, +3 authors H. Li
  • Published 1989
  • Chemistry, Medicine
  • Yao xue xue bao = Acta pharmaceutica Sinica
Three diterpenes including a new compound were isolated from the whole plant of Siegesbeckia glabrescens Mak. The new one was named as neodarutoside and its structure was elucidated as ent-3 alpha, 15,16-trihydroxy pimarane 3,15-bis-(beta-glucopyranoside) based on the spectral evidence and chemical transformation. The other two were darutigenol and darutoside. Darutoside possesses the activity of termination of early pregnancy in experimental rats at a dosage of 20-40 mg/kg. 
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