[Studies of the correlation between fragile sites and giant panda's breeding problem].

@article{Wang2001StudiesOT,
  title={[Studies of the correlation between fragile sites and giant panda's breeding problem].},
  author={Xiaojing Wang and Xiao Xiong Wang and Yee Fan Tan and Ying Juan Wang and Xun Zhang Wang and Hong Wei Chen and Guishan He and Lianhua Fei},
  journal={Yi chuan xue bao = Acta genetica Sinica},
  year={2001},
  volume={28 7},
  pages={
          621-7
        }
}
An unique culture system has been established which can effectively indicate fragile sites induced by BrdU on giant panda chromosomes. After we cultured the lymphocytes of giant panda for 96 hours and treated it with low concentration of BrdU (10 micrograms/ml) for only a short time (4 hours), the areas of high-frequency-expressed fragile sites were successfully located on the centromeres of No. 2 and No. 12 chromosomes. After statistic analysis, we found that the frequency of fragile sites on… CONTINUE READING

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