[Structure-activity relationship of diosgenin derivatives as Bcl-2 antagonists].

Abstract

The purpose of this paper is to clarify the structure-activity relationship of anti-tumor activity of diosgenin derivatives in vitro. Study has found that diosgenin can inhibit the reproduction of tumor cells by inducing apoptosis and the main target spot of this effect is Bcl-2. Based on the characteristics of pharmacophoric points' of the three… (More)

Topics

  • Presentations referencing similar topics