[Spinocerebellar ataxia 1--clinical study of 17 patients in a large pedigree].

@article{Sasaki1993SpinocerebellarA1,
  title={[Spinocerebellar ataxia 1--clinical study of 17 patients in a large pedigree].},
  author={Hiroshi Sasaki and Akemi Wakisaka and Tsukasa Koyama and Takeshi Hamada and Katsuji Shima and Kunio Tashiro and Keiji Hashimoto and T. Miyagishi},
  journal={No to shinkei = Brain and nerve},
  year={1993},
  volume={45 6},
  pages={502-8}
}
We studied a large pedigree with dominant spinocerebellar ataxia, genetically and clinically. At now, 27 members over 5 generations have been affected. Linkage study for the disease locus to D6S89 in a total of 44 individuals showed maximum lod scores of 3.99 at theta = 0.000. This result indicates that the disease locus of this pedigree locates near D6S89… CONTINUE READING