[Spectrum of gene expression of a multi-drug resistant leukemia cell line with high tumorigenicity in nude mice].

Abstract

OBJECTIVE To investigate the mechanism of multi-drug resistance of K562-n/VCR cell line with both bcr-abl and mdr-1 expressions by clustering analysis of differential gene expression profiles. METHODS By DNA microarray technique, genes differentially expressed by K562-n/VCR and K562-n cell lines were identified and analyzed. RESULTS DNA microarray… (More)

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