[Somatic cell nuclear transfer and centrosome inheritance].

  title={[Somatic cell nuclear transfer and centrosome inheritance].},
  author={W Du and Hua-Bin Zhu and Hai-Sheng Hao and Dong Wang},
  journal={Yi chuan = Hereditas},
  volume={30 8},
The developmental competence of embryos cloned from somatic cells depends on the cellular event and molecular process, such as separation of chromosomes and reorganization of spindle after nuclear transfer. Centrosome, the main microtubule organizing centers in a cell, is crucial for reorganization of spindle and normal separation of chromosomes during mitosis. Aberrant of centrosomes will lead to aneuploidy of blastomere and developmental failure of embryo. This paper expounded the situation… CONTINUE READING